Sorry, I haven’t…

But I did a ton of research on neuromodulators (aka antidepressants) for pain and GI symptoms. I know it’s a traditional antidepressant (as opposed to SSRIs and SNRIs), so it typically has more side effects than the new we neuromodulators (dizziness, dry mouth, sleepiness, etc.)

But when it’s dosed for chronic pain, it’s usually given at a smaller dose than the dose used for a mental health condition. It may be less likely to experience side effects at the smaller dose, so I was told.

Sorry, I know you probably already Googled all this before. Maybe others will he able to share the ore experience.

I think it’ll probably depend on how risk averse you are. I’m extremely sensitive to medications, so I gave up on taking the antispasmodics (Lyrica, gabapentin) and neuromodulators (aka antidepressants).

I got much more relief and leverage out of chronic pain physical therapy such as Graded Motor Imagery or a chronic pain program, but I know it’s not for everyone.

But the reason I replied was since you listed so many medications you’ve tried, I wanted to mention I take low dose naltrexone (LDN) for chronic pain, in case that may be something you’d want to look into if it turns out the side effects for the nortriptyline concern you.