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Changing chemo regimen after 4 cycles of Folfirinox?
Pancreatic Cancer | Last Active: Aug 10, 2023 | Replies (20)Comment receiving replies
Hello. I was scheduled to have Folfirinox 6 weeks after I had the Whipple procedure - stage 3 pancreatic adenocarcinoma. I had 1
Folfirinox treatment in the hospital but my reaction to it was so severe that I wasn't even able to complete the 2 days at home with it after the infusion at the hospital. I had terrible vomiting and a fever right away. I refused to take anymore and the oncologist switched me to gemcitabine and abraxane. which I tolerated for the 6 months that I was on it.
Since then. I have a new oncologist who told me they could have adjusted
The folfirinox cocktail, but my original oncologist never even mentioned that. The gemcidibine/abraxane wasn't too bad until about the last 6 weeks when the nausea became worse and I had a fever one day per week. Also, I could only do the chemo every other week because it really affected my
white blood cells.
I dont know if this helps you, but I know what you're going through.
God bless.
Replies to "Hello. I was scheduled to have Folfirinox 6 weeks after I had the Whipple procedure -..."
Yes, the gemcidibine/
abraxane made my white cells dip below normal, so I was given it 2 times
a month. I never had to have neulasta.
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lilliejane2 - Thanks for your input. Yes, it does help. Your severe drug reaction is different than mine.... I've had neither vomiting nor fever. I assume your white blood cell count was low, and the reason for getting the Gemcitabine/Abraxane every other week rather than once a week. My WBC has been rising. As of a few days ago, it was 22.3, two times above the upper limit of normal values. This apparently due to the Neulasta injection I received following my second and third infusions.