I guess I've been lucky not having any problems being on 20mg of Crestor. You might ask your doctor about doing alternate day dosing (ADD). Some people find relief from that. I've read a few articles that stated your cholesterol levels take many weeks to go back to where they were before starting a statin, so doing ADD "shouldn't" have much impact in your cholesterol levels (but of course, check with your doc). And articles I've read stated that there's not a significant difference in cholesterol levels between groups doing ADD and groups doing EDD (every day dose). Might be worth discussing with your doc.