No hand tremors or numbness but I do have trigger finger in my right pinky and arthritis in my right wrist which is possibly carpet tunnel. I see my plastic surgeon for in a few weeks. I did however make the decision to stop Arimidex. My other symptoms of memory loss, 13% bone loss, anxiety , depression affected my quality of life to the point I needed to find an alternative, I am now seeing an MD/Naturopath who is part of the same Sutter Health organization my allopathic oncologist is part of. I just recently had my 3 estrogen levels checked which I don't have results for yet but these figures will determine our course of action. Am taking a myriad of natural AI supplements now. Stopped Arimidex on June 6ths and my mood is lifting and feel like I can actually fight this disease better because I have more energy for exercise, etc. Even brisk walking an hour a day 4xweek lowers bad estrogen by 19%. I believe our brains, bones, heart, muscles, etc need estrogen (the good kind which is not contributing to our cancers).