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MAC nodules

MAC & Bronchiectasis | Last Active: Jul 27, 2023 | Replies (54)

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@sadair20

My allergist ordered blood tests that revealed Aspergillus. I don't know what the count was but he wanted to put me on Trelegy to see if that would knock down inflammation potentially contributing to my bronchiectasis. I do have 3 nodules, however 2 are too small to biopsy and the 3rd is right next to my heart so I'm trying to avoid biopsy there.
I haven't taken the Trelegy yet because 1) I don't really want to inhale steroids if I can help it and 2) from what I've read I should be using an antifungal, not a steroid. Does anyone have experience with Trelegy and Aspergillus? Would it make sense to take it to see if it would decrease the size of the nodules?
This entire lung thing can be so confusing.

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Replies to "My allergist ordered blood tests that revealed Aspergillus. I don't know what the count was but..."

Hmm, Were these blood tests or sputum samples? If the aspergillus is in your lungs, it is time to go back to your pulmonologist - they are more experienced in treating bronchiectasis and related infections. Also, they may have better idea whether your lung nodules are characteristic of a MAC lung infection. Definitely if there is evidence of lung infection, it is good to avoid steroids which depress the immune response.
Does your pulmonologist have you doing airway clearance?
Sue

I was on Symbicort for 3 1/2 years, aspergillus developed last year. It got worse until I stopped the Symbicort after a NJH Dr added Spirivia. Once this happened I started getting better. I now take Voriconazole. I will never take a steroid again.

So that is odd to me! I was diagnosed with invasive aspergillosis last summer after a lung procedure. A blood test that picks up aspergillosis is probably not good. I am hoping it was an allergy blood test that showed you are allergic to mold - specifically aspergillosis. Trilogy will not help aspergillosis in your lungs. It may be good for your asthma, but if you have aspergillosis get yourself to an infectious disease doctor asap!!! You will be put on something like Vfend or Cresemba - after it is effectively diagnosed. (@irene5)