PSA can vary, particularly with USPSA. Here's my clinical history, as you can see, while I was on the standard test, measure to a single decimal point, labs would say undetectable, >.1. When my urologist switched me to USPSA. it was all over the map, up, down...

My urologist didn't have an explanation but we both agreed that single results were not triggers for imaging or treatment decisions, rather trends, specifically three continuous increases spaced 2-4 months apart and imagining when PSA between .5 and 1.

We met that criteria this year, we imaged using Plarify, it located one PLN, we did five SBRT toi ikt and decided on six months of Orgovyx for micro-metastatic disease.

There is discussion though not necessarily agreement on USPSA and what the values mean.

Consider discussing with your medical team about trends vice single results when using USPSA.

Kevin

Kevin