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How long before relapse occurs or ADT fails?

Prostate Cancer | Last Active: Aug 6, 2023 | Replies (27)
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@philipbrachko

My research on this is all over the place. Seems to be very subjective...i.e. too many variables. Also a lot of different types and ways of going about ADT. I have different doc's with different viewpoints. There are a ton of case studies out there, If I need to go back on ADT, like to try Zytiga 6 months on and 6 months off. This way I stretch out the effect, before becoming resistant. Zytiga works by binding to the cancer cell ,starving it of Testosterone. Hopefully preventing spread.

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Replies to "My research on this is all over the place. Seems to be very subjective...i.e. too many..."
komurph | @komurph | Jul 23, 2023

zytiga is it oral or injection
how is ur fatigue

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wellness100 | @wellness100 | Jul 24, 2023

Thanks for both replies above. I come to more or less the same conclusion from scanning the webs. The majority seems to be 5+ years old and counting. Most docs do not seem to want to stick heads out, for understandable reasons. Those who do, with the ones such as Dr. Scholz tend to provide low numbers, for understandable reasons.
One issue is they quote the clinical studies. The small print in these studies is their cut off point is PSA 0.5. But from some rare studies, and for practitioners such as Dr. Scholz,, their cut of is PSA 0.2. < 0.2 the survival rate for 5 and 10 year are about 85%.
It appears, and Dr. Scholz does articulate that, the outcome for those below 0.2 is very different. For under 0.1, Dr. Scholz's experience or opinion is more like 10 years.
So there seems to be a gap, and a fairly big gap .

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