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@naomid

My endocrinologist will not allow me to take for teo or Tim Los because I had radiation to the breast many years ago. She said it would be too great of a risk. Is that no longer the case? My doctor said that my spinal column which was largely irradiated would be too susceptible to bone cancer. Do you have any updated data that indicates otherwise?

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Replies to "My endocrinologist will not allow me to take for teo or Tim Los because I had..."

P.s. please excuse spell check errors. That should have said Forteo or Tymlos.

@naomid radiation is still on the websites for these meds as a contraindication. My endocrinologist is flexible. If I were you I might ask about doing just 6 months, since that is when Forteo and Tymlos create the most bone growth. For Evenity I was told 4-6 months of maximum bone growing. I have no idea what a doc might say!

Here are two sources of info; I am sure there are more:

https://www.healthline.com/health/drugs/tymlos-side-effects#side-effects-explained

"Due to the possible risk of bone cancer, doctors will usually not prescribe Tymlos for people who are already at high risk. This includes those who have:
a metabolic bone disease besides osteoporosis, such as Paget’s diseasea history of bone cancer or another cancer that has metastasized (spread) to the bones
received radiation therapy or external beam treatment that involves the skeleton."

However for both there may be exceptions:

See the conclusion of this study:
https://pubmed.ncbi.nlm.nih.gov/34608566/

"Conclusion: Despite radiotherapy being a relative contraindication to teriparatide use, there may be a role for teriparatide in select cases where osteoporosis is complex and severe and where other treatment options are not suitable or have been exhausted. The risks vs. benefits of prescribing teriparatide in this population should always be carefully considered, and both the patient and treating oncologist should be educated on the potential risk of osteosarcoma development when teriparatide is continued during radiotherapy."