Hi, I am 76 and was diagnosed with mac 2/22 and started the big 3 8/22. I had to stop ethambutal in April of this year as I failed twice the field view eye test and my eye Dr took me off the med immediately. 4 months later I was able to pass the test. I remain on azithromycin and rifampin with some nausea and diarrhea but luckily have not had any fatigue but do have insomnia and sleep only 3 to 4 hrs a night and no naps during the day. Everyone is different but it is worth it to take the meds. My cough is almost gone but I still have nodules found on cat scans but never cavities. I am now waiting for my last 3 sputim tests to see if negative. Previous once were 2 negative 1 positive. Since I have been on meds a year next month if any of the next tests are positive my meds may be changed. So I am looking into another chapter in this terrible disease. You just need to keep going and don't give up even at our ages. Good Luck in your journey and don't give up!1