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Anastazole for breast cancer and memory loss?

Breast Cancer | Last Active: Aug 15, 2023 | Replies (66)

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@ginip

I researched “brain fog” and “muscle and joint” side effects. I was curious what else besides estrogen being blocked from the breast to help prevent breast cancer where else was being blocked from estrogen

It turns out that the benefits of Anastrozole which I was taking actually robbed estrogen from my brain and joints/muscles.

It explained so much to me re my muscle and joint issues. I was denying my muscles and joints of something they vitally needed - estrogen!

The Brain Fog was more subtle to me until I read my research further. My basic personality had changed and I thought it was depression from my continuing and progressive joint pain. It was more than that. Realizing how the brain needed estrogen gave me additional very important considerations as I entered a 3 month hiatus from Anastrozole sanctioned by my oncologist.

The results have given me my life back on some very consequential levels. I have another month on my hiatus and will then have a much more knowledgeable conversation with my oncologist.

Bottom line here is (in my opinion) Anastrozole (that I have been taking) doesn’t CAUSE brain issues and muscle/joint issues - it INVITES them. I was told continuously that it wasn’t Anastrozole that caused the pain I was experiencing - it was arthritis.
When researched it provided the more accurate explanation -
The lack of estrogen from Anastrozole was INVITING arthritis! My knee has come back to normal and my brain to appreciate the value of focus once again.

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Replies to "I researched “brain fog” and “muscle and joint” side effects. I was curious what else besides..."

I’m waiting for results of MRI to find out once and for all what is causing my back pain. Hopefully it won’t b anything suspicious but the I’m in no man’s land at tge mo - is it side effects to Anastrozole and rivaroxaban, arthritis, or something else. I WILL change my meds irrespective of my result. I now have Breadt Cancer Nurses in Magnolia Clunic in York, on my side instead of depending on my gp surgery. So fingers crossed…. 🤞🏻🤞🏻🤞🏻🤞🏻Nothing suspicious will b found x

Well written i often thought if estrogen has a play in my memory issues. I’ve been told I have moderate dementia starting ( only 69)😢
I have a lot of white matter on brain. Is it also due to diabetes? Scares me to think this. I still feel chemo played a part of my diminishing memory. Is there more articles on blocking estrogen on prevention memory loss?

@ginip your post has great info. How long have you been on Anastrozole? I was on for 2 1/2 yrs. I had taken vacations from the med several times for a month and then 2 months I believe. The relief from hip pain & fog (looking back I was not myself, I describe as a fog over me) wasn’t really improved. After deciding to stop Anastrozole, it took at least 6 months for me to be back to myself. The hip pain was very bad. I could not hardly get in or out of the car or walk.
Have that discussion w/ your oncologist. It would be good to keep a daily log of how you feel each day. It’s difficult to separate out everyday ‘how I feel’ from ‘how I feel being off med’. Blessings to you.