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Has anyone had PC that is very aggressive and a very low low PSA?

Prostate Cancer | Last Active: Jul 23, 2023 | Replies (47)
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@sam60

Yes stay as positive as you can. Lots of up’s and down’s . Let me know how it’s going. Also what Mayo had to say about low PSA with high grade cancer.
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Replies to "Yes stay as positive as you can. Lots of up’s and down’s . Let me know..."
round5 | @round5 | Jul 23, 2023

I can tell you. You can have a very low or even undetectable PSA and still have aggressive cancer show up on PET scan. Although rare it does happen that’s why yearly scans are so important with a high grade cancer especially when you have had multiple reoccurrences and treatments as I regardless what your PSA is. I have a neuroendocrine type of the disease most likely caused from my multiple reoccurrences and treatments. PSA was 0.62 when it showed up.

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