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@val64

One more thought. Paxlovid includes two drugs: nirmatrelvir, which actually inhibits Covid, and ritonavir, which was designed against HIV, but is included in Paxlovid because it inhibits a liver enzyme that breaks down other drugs, including nirmatrelvir. You don't know whether the apparent effect on your symptoms requires both drugs or whether ritonavir alone might have the same effect. If it's not currently possible to try Paxlovid, it might be worth asking a Dr. to prescribe ritonavir alone. That is almost certainly legal, and is probably even reasonably priced.

One reason Paxlovid could have helped you would be if the ritonavir increased the level of some other drug that you're taking. The doctors probably wouldn't be thrilled if this is what's going on. But if it is, it would be nice to know. Or it could be that there is some naturally occurring compound whose metabolism is affected by ritonavir, and that is what is improving your symptoms.

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Replies to "One more thought. Paxlovid includes two drugs: nirmatrelvir, which actually inhibits Covid, and ritonavir, which was..."

What an interesting idea to try ritonavir alone. I'm going to ask my doctor about this. Have you heard of anyone trying it?

I am not on any medications except occasional ibuprofen for my osteoarthritis, fibromyalgia, CPPD arthritis (constant inflammation from calcium deposits in soft tissue and joints). I felt almost completely pain free after the first dose of Paxlovid. I googled, and sure enough, I'm not the only one. My first thought was-Is it suppressing Epson Barr virus?