I’ve read that this is possible:

“ Evidence supports the idea that statin therapy not only reduces cholesterol levels but also changes existing plaques to make them less dangerous. As part of this process, the plaques may become more calcified—and thus, the calcium score goes up. An increasing calcium score with statin therapy, therefore, may indicate treatment success, and should not be a cause for alarm.”
https://www.verywellhealth.com/statins-and-your-calcium-scores-1746355