Hello- I am 81 years old and I very much empathize with your situation and your wish to lose some weight. I have a disease called Panhypopituitarism which means I have no active pituitary gland. Therefore I have to take replacement hormones for all those that my absent pituitary gland no longer provides. When my illness first appeared I was besieged with all kinds of health issues such as severe osteoporosis, hair loss, sixty pound weight gain, etc. Since I’ve had this disease for over twenty years, I’ve been trying all that time to lose at least some of the weight but to no avail. I don’t have much appetite so I’m always mystified as to what inside my body doesn’t work as it should. Family members say it’s because I don’t exercise enough, and this is probably true in that my osteoporosis caused a lot of trouble in my back. Several years ago I finally consented to have back surgery but unfortunately the surgeon made an awful error and I ended up in worse condition than when I went into the operating room. While I was ultimately compensated for the error, dollars don’t eradicate nasty pain. How does a person do the requisite exercise to lose weight if one is seriously hampered by pain? Like you, any weight loss is close to impossible for me, although I did lose a couple of pounds after I had cardiac surgery (TAVR aortic valve replacement). My best wishes go out to you and I hope you stay in touch.