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Undiagnosed Autoimmune Disease - No one will listen to me
Autoimmune Diseases | Last Active: Dec 30, 2024 | Replies (180)Comment receiving replies
suetex, Yes. I was having peripheral neuropathy symptoms in my arms & legs....especially when sleeping. My primary was not aware that I had been put on Naltrexone by my Endocrinologist. When I went to see my primary physician for the symptoms he asked if I was on any new medication. I told him about the Naltrexone. He wasn't familiar with Naltrexone and looked it up on his ipad. He told me to get off the drug immediately. Two of the side effects were migraines (which I already suffered from) and peripheral neuropathy. I will add, that my B12 was low and that can also cause peripheral neuropathy symptoms. I came off the Naltrexone and got B12 injections and the peripheral neuropathy symptoms went away in 2 weeks and for that i am grateful. I have to say I have had low B12 again (I am presently on B12 injections) and did NOT have peripheral neuropathy symptoms at all this time. I cannot be 100% sure that it was all Naltrexone, but, I have a gut feeling it was. I hope it works for you. Blessings.....
Replies to "suetex, Yes. I was having peripheral neuropathy symptoms in my arms & legs....especially when sleeping. My..."
I was born with migraines but manage to control them later in life and the LDN did not trigger them. I'm sorry you are one of the unlucky few. It seems to bear lots of promise to those of us with unruly immune systems Best of luck...
Unfortunately the broad effects of B12 deficiency is not well understood in the medical profession. Part of the reason is that a better understanding of B12 absorption process has only become developed in the last 5 years. Add to that the recently understanding that the absorption process declines with age and the result is rampant under diagnosed and under treated B12 deficiencies.
My own treatment experience with B12D has ranged from monthly injections of 1 cc of B12 starting about 15 years ago to the precent 0.5 cc injections every 5 days! The increases in injections was necessitated as my symptoms evolved from Anemia/Fatigue in the beginning to short term memory and balance issues
recently.
Because my B12D was triggered by Celiac Disease gut damage my B12D adsorption problems were more widespread that just the symptoms listed above and the B12 injections have helped significantly in managing them in part because B12 is a powerful anti-infamatory!
Chris47 -
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It seems unlikely that the low dose Naltrexone would cause peripheral neuropathy. A number of people who developed peripheral neuropathy after Covid or the Covid vaccines are taking low dose Naltrexone and it's helping their neuropathy. The B12 deficiency would seem to be the more likely cause of your peripheral neuropathy. As you probably know, vitamin B12 deficiency is a known cause of peripheral neuropathy.