← Return to CEA and CA19-9 Results as Predictors of Treatment Outcome

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@kjc12

My husband was about 80% recovered from Whipple when they urged starting chemo. He is having the same combo as you and each one has been hard. This past Tuesday was #7 and it has hit him like a ton of bricks. Wound up in ER yesterday from vomiting 4 times plus diarrhea. They did a scan to check for blockage. Scan came back fine. Dehydration has been a constant occurrence. He has lost so much weight it’s scary now. How you ever handled 12 rounds is beyond me. I don’t want him to continue if it’s ruining any form of daily life.
How did you do it? Eating and drinking is so hard for him, breaks my heart.

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Replies to "My husband was about 80% recovered from Whipple when they urged starting chemo. He is having..."

Is there any way they can lower the dose of the modified Folfirinox? Originally my MD was going to give me the full dose until he realized I'm 70. He lowered the first cycle to 80 percent of the full dose, and even at that level it really laid me low with dehydration, diarrhea and nausea. Beginning with cycle 2, the dose was lowered to 60 percent of the full dose. Each cycle has gotten progressively easier in terms of side effects, appetite and even weight gain, and I now have several days at the end of each cycle where I feel pretty much like I used to before all this started.

I had been on Folferinox and now presently on Gemzar/Abraxane. For each treatment, excessive side effects were handled with either time off or dosage reduction or both. Have these options been considered?