Thanks for the reply. One oncologist told me at the beginning of radiation that I would also be taking Lupron (later switched to Eligard by Mayo) for 36 months - "if I could handle it." I asked what was meant by that and now I know. There is no way I can continue to live like this for 36 months. I hear about men going many years on ADT and it not affecting them like it affects me. It's interesting how it affects everyone differently. I'll certainly ask about monthly injections to see if that's a viable option. Thanks for the tip!

65 yo male, Brac 1 positive w/ breast cancer & mild prostate cancer. Have endured monthly Lupron shots for 6 mo. while taking anastrozole daily. Also developed L4-L5 spinal stenois and osteoarthritis in both hips and knees. 5cm breast tumor shrinking but with every Lupron shot groin & thigh pain getting worse and worse. Very sexually active before Lupron and know not in 5 months. On a walker 95% percent of time and cane the remainder. I'm still working full time and quality of life is dismal. No pain or discomfort from cancer but leg and hip pain very debilitating. Considering going against Dr. and stopping Lupron & anastrozole after tumor removal scheduled for February 2025. Dr. had suggested Lupron for another 5-10 years after surgery. No way.