I'm on Eligard. I have Stage 4, advanced, agressive, Gleason 9 PC. After nine months, I can barely get up from chair because of stiffness and pain in my legs, have some pretty good hot flashes about once an hour, have lost some muscle, lots of fatigue. I also have heart failure so the oncologist is considering stopping the Eligard as it can cause heart attacks. Leuprolide seems to me to be a good drug/bad drug and everyone has to weigh their own risk/reward status with it. I'm really wondering if I should stop the drug (regain some lifestyle normalcy) and hope the PSA stays low or continue another nine months with the side effects that are changing my way of life. Big decision ...