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@govisri

If it is antibody mediated, why the docs not recommending immunosuppressive drugs like tacrolimus, cyclosporin, or cellcept?
Also, I would like to know if anybody had PLASMAPHERESIS done to remove the offending antibody. Thank you.

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Replies to "If it is antibody mediated, why the docs not recommending immunosuppressive drugs like tacrolimus, cyclosporin, or..."

Great questions. I'll be interested in reading responses.

@govisri, I'm thinking the answer to your first question is a little complicated and has some dependencies. Even though this article is specifically about Lupus, I think this is the basic reason but then I'm not a doctor and have no medical training.

"Because immunosuppressive drugs put down the immune system, people taking them are at an increased risk for infection."
--- Treating Lupus with Immunosuppressive Medications: https://www.hopkinslupus.org/lupus-treatment/lupus-medications/immunosuppressive-medications/.

There is another discussion on Plasmapheresis that you might want to read through here:
--- Plasmapheresis - anyone had success?: https://connect.mayoclinic.org/discussion/plasmapherisis-anyone-had-success/