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Lesions on the brain and autoimmune disease

Autoimmune Diseases | Last Active: May 15 2:14pm | Replies (54)

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@gardrums123

My husband also had lesions. He started with an unsteady gait and double vision which is what MS can present. At first they said it was lymphoma hiding somewhere and aggressively pursued that. It turned out that was not the case. They sent him home from the hospital after numerous MRIs, a brain biopsy and several lumbar punctures. They kept insisting it was between MS and Lymphoma. They said the lesions he had did not coincide with how MS presents lesions so they were very confused.
In November he had a relapse where he couldn’t walk at all. He went to Mt. Sinai in NYC where they again did numerous MRIs and blood and spinal taps. They sent all of the fluids to Mayo and they diagnosed it as GFAP.
He was put on high steroid treatment and anti rejection med and is now tapering them. They don’t know much at all about his disease, so we don’t know what the outcome will be when he is totally off the steroids.
I hope for your sake you won’t end up with this. Good luck to .

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Replies to "My husband also had lesions. He started with an unsteady gait and double vision which is..."

May I ask did he ever have bad joint pain or a flu like feeling? The neurologist said the same thing about my scan as well, that my lesions are not a normal pattern for ms. She did do blood work and said my ANA were positive and it was speckled pattern and based off that blood test right there she said that's why she thinks it's rheumatoid.

I had a similar first diagnosis in March plus a "flare-up?" on July 5 and ended up worse. Lots of steroids, finally a diagnosis??? MOG antibody autoimmune disorder. Neuro found it. Had same tests originally as your husband. They ended up figuring out it was MOG? I don't know as just beginning the diagnosis process and learning about it. I do not know what Mayo would do. For reference, I am female and 62.