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DiscussionTrying to determine long term prednisone versus other prescriptions
Polymyalgia Rheumatica (PMR) | Last Active: Aug 3, 2023 | Replies (33)Comment receiving replies
Replies to "I understand what it's like to try to make these decisions. After 18 months on prednisone..."
Prednisone is known to "redistribute" fat. I have a "beer belly" and people didn't believe me when I said that I didn't consume alcohol.
I had some liver issues while on prednisone. It was noted that I had non-alcoholic fatty liver disease (NALD) on a CT-scan that revealed kidney stones were causing severe abdominal pain and nausea.
I took methotrexate for nearly 2 years in addition to prednisone while my liver enzymes increased. I was progressively getting more nauseated so methotrexate was discontinued even though I was able to decrease my prednisone dose.
I'm having a slight increase in my liver enzymes while taking Actemra but I'm not nauseated. My rhematologist consulted a liver doctor to see if I could continue taking Actemra. The determination was that my elevated liver enzymes on Actemra were more likely caused by NALD.
It wasn't necessary to stop Actemra since I wasn't nauseated or otherwise symptomatic. The liver doctor just said my liver enzymes should be monitored so they don't get too high.