I am also looking at this. I think to modernize it, they could give us a month of LU-177 pluvicto kind of thing instead of ADT (as far as I know this is not offered). In many cases ADT is just above noise in the data if it would help, some people maybe, others maybe or probably not. At least for me I would rather do proton then a short duration LU-177 kind of thing, that over the old tech ADT that only helps a few and hurts a real lot of people.

I pray about everything and I just don't have peace with the OLD hormonal treatments with significant side effects.
Thank you for your input, I haven't studied LU-177 yet.
GOD is in charge... 🙂

My experience with ADT hormone therapy Orgovyx was not that bad.
BCR after RP led to salvage radiation together with 4 mos Orgovyx.
Different protocols for different Drs/patients, but a 4 - 6 mos ADT course appears common.
I was opposed to ADT until my Rad Onc said adding ADT to my radiation would add 20 percentage points to my possible outcome.
Sold. Did not like it; would do it again. In for a penny: in for a pound. I'm trying to put this evil thing into deep sleep.

I had proton without ADT. I was an otherwise healthy, very active 74 year old who did not want some of my last good years potentially ruined by ADT. If my life expectancy was shortened somewhat but quality was increased, count me in. One of the radiologist that I consulted with estimated that while deleting ADT might result in a 20% worse outcome, perhaps a 15% better outcome would occur from avoiding all the other health impairments that could occur from ADT. One of the specific considerations for me was the amount of dementia in my family on my fathers side. It is important to state that this radiologist estimate was for my specific case and personal considerations!
I did all the recommended things( bone scan, mri, PSMA pet, decipher and pathology second opinion) as well as consulted with urology oncologist, photon radiologist and two proton radiologists. My Gleason was 4+3 (2 cores) and 3+4. ( 3 cores) out of 10 samples. My PSA was 8.9. Post-treatment PSA was 2.9, 2.3,4.9 ( spike that happens sometimes) and 1.7. I completed proton treatments a little over a year ago so only time will tell if this was the right decision but you make the best decision for you and don't look back.

I'm 73 ,been on ADT, Zytiga 6 months and Eligard for a year, my side effects were minimal. Loss of strength and muscle, and ED. Some brain fog setting in the last 2 months. Continued to workout, do breathe work, meditate . I was ok with the side effects, because of the great results, PSA < 0.04 for the last 10 months, and everything has shrunk down to normal size, having RALP next week.

Bandit 11: Your analysis and choice (for you) makes perfect sense to me.
Best wishes for a good outcome.

My first consultation the Radiologist/Oncologist were recommending hormone treatments. Then they said would not recommend if have cardiovascular issues. I have heart failure so they said no hormone treatment. I was listed as intermediate risks because only 1 of my biopsies was 3+4 all other biopsies were 3+3.

I then had a Decipher test done. It came back as low risk. The original consultation Oncologist then said hormone treatment not recommended only curative radiation. But this provider did not offer proton just photon.

I chose to go to UFPTI which does have proton. So I am one of the ones who did have proton treatments without hormone treatment. I did not want hormone treatments unless absolutely necessary. I am an avid exerciser and would affect this along with being a heart failure patient.

Did you have a Decipher test? I would really recommend it. It gives a more precise diagnosis. Also make sure you get second opinions and not just a single source. There are also many excellent sites to read up on treatments and get professional medical advice which allows you to be an informed patient and be able to question and asked questions.

I did a post that gave my experience with this. I also got the suggestion of doing it for a month to see how I feel. Please read my post. I know it is really hard to know what to do and you get so many telling you different things. That is why it is so important to have second opinions and research different treatments. Not one treatment is best for all and really depends on your personal health and specific degree and type of cancer.

I am done with my treatments. I did have the side affects mentioned I would get but none of them required medications or procedures. I did have some mild fatique but was nothing I could not deal with and had subsided now two weeks later. Being an avid bike rider I was not able to ride because of Space/Oar. So when I started back OMG were my legs out of shape and boy did I get sore.

Much appreciated guys... I have always been super sensitive to any drugs and even supplements.
I don't see the upside to feeling horrible for years in my 70's.
I'd rather, pray, kick ass and get a new horse to compete in 50 mile endurance races thru the Sierra Nevada Mountains.
You can't unscramble eggs and I sure don't want to waste the quality of my life on a percentage.
I feel great right now and I can't wait to start working out again after the 2nd biopsy.
Just waiting for the results. Blessings,

Hello, At age 68 and having gone 28 radiation treatments in 2022 along with one 6 month injection of Lupron. The Lupron really messed with my entire being. Very depressed, hard to focus, suicidal thoughts on a regular basis. I cant actually see any reason for me to ever consider that course of treatment again. Today about 7 months after the radiation I am beginning to feel more like normal with my last psa being in June at 0.12. I have decided that should the cancer rear its ugly head again I will take my chances without any additional adt. Other that still being very tired and needing a short nap in the afternoon I finally have ambition to get things done again! I hope that other men have has better reactions to the Lupron than I have. Best of luck to everyone fighting this battle.