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Anyone out there on Guanfacine?

Post-COVID Recovery & COVID-19 | Last Active: Jan 29 1:24pm | Replies (60)

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@ripley

Regarding LDN, how long did you stay at one dose before going to a higher dose. Did you increase by .25mg each time? Also, any side effects? I started LDN (for fibromyalgia that started 5 days after having Covid) five days ago at .05 but had worse body pain was advised to skip a day and restart at 1/4 of that, or .125. At this low dose, I'm not sure if some increased pain is a side effect or not. Yesterday I had some nausea and flu-like symptoms, which can be side effects that are supposed to subside after a few days on the LDN. I'm hoping it works for me.

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Replies to "Regarding LDN, how long did you stay at one dose before going to a higher dose...."

Yes, I just ended up increasing by .25 mg each time. I stayed at .25 mg for 2 weeks, then increased to .5 mg, and so on, until I reached 4.5 mg. That was the goal my PCP and I agreed upon.

If I experienced side effects for 2-3 days, I dropped back to the previous dose for another 2 weeks, or like you I suppose I would also have gone down to 1/8 of a milligram. Then, I'd moved forward again.

The only thing I did to titrate faster was that later in the game, I waited only 7 days before increasing the dose. I don't really remember when I started doing that, though. It might have been after I got to 2 mg or so. I still followed the same template; if I had side effects that lasted for more than 2 days, I dropped back to the previous dose. But that is my usual model for how to incorporate new interventions for my body though. It's how we manage my central sensitivity syndrome.

The only side effects I had were feeling too energized/alert and difficulty sleeping, which is are known sides effects. I believe GI symptoms and flu-like symptoms may also be known side effects. I didn't have increased pain.

I hope it helps you too.

Please be careful of your math. If you really started at 0.05 and want to reduce it by 1/4 you should have ended up at 0.0125 not 0.125. Perhaps this is only a typing error. I am not trying to nit-pick your post, but to alert you to a possible confusion. We are all in this journey together, trying to achieve mutual support. I wish you well.