I neb with aerobika 29 minutes in the a.m. before eating anything. And, I cough up a good amount of both clear and yellow mucus. I follow that with 20 min with my compression vest. I follow this 2x routine daily. My second nebbing session has me coughing up about the same amount of mucus. The timing of my 2nd nebbing session varies. Sometimes I do it around 4 ish but, as I mentioned, if I am feeling esp cough prone, I'll wait and do it closer to bed time. Some days are better than others. Today I tried something different while nebbing. I stopped after about 10 minutes and did some huff coughing. and then resumed the nebbing. I think that helped get even more gunk out. Best of luck to you, Irene.