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How long did your doc have you on Tymlos?

Osteoporosis & Bone Health | Last Active: Oct 6 11:16am | Replies (53)

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@windyshores

@omgirl the P1NP and CTX. Blood tests done early, fasting.

From McCormick's book: "If you've been treated with denosumab (Prolia), sequencing to teriparatide (Forteo) or abaloparatide (Tymlos) or even romosozumab (Evenity) will increase cortical bone porosity, accelerate bone loss, and heighten risk of fracture. If your doctor suggests this type of sequential therapy, please get a second opinion." My endo says the same thing.

Not sure how this applies to someone who was off Prolia and then on again for a short time, if that is your situation. It seems we all have to take a bisphosphonate, preferably Reclast, at some point to lock in gains, or we lose what we gained.

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Replies to "@omgirl the P1NP and CTX. Blood tests done early, fasting. From McCormick's book: "If you've been..."

Sorry, I noticed an error in my previous reply Re: Prolia. I was off Prolia for 18 months or a bit longer and did NOT go back on — Was supposed to say off Prolia for 18 months before started Tymlos! In between I was taking Evista for about one year but it didn’t help and my DEXA was down approx 10% so we discussed Tymlos since my sister mentioned as she had already taken it. Unfortunately I’m allergic to bisphosphonates so that’s not an option and I was also diagnosed with jawbone necrosis over a year ago which I was treated for. A side effect of both bisphosphonates and Prolia so not sure what I’ll do after Tymlos. Perhaps something new or more valuable research will be available within the next couple of years