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Letrozole and checking estrogen levels
Breast Cancer | Last Active: Mar 16 3:05pm | Replies (94)Comment receiving replies
@cherziggy many of us tolerated these meds pretty well. I hope you will at least try 🙂 And in my experience the body adjusted so I think it is good to give it a little time before deciding whether to stay on. Just my opinion.
@californiazebra I don't know why side effects would be different at 100% versus 20% dose. I just don't understand but a doc could explain. To me, if the AI is effective, that means it has reduced estrogen below detectable levels. Side effects would be from the estrogen suppression, no matter what the dose. So wouldn't side effects be the same at all levels of medication, if it was working?
My doc did say we can take them alternate days- I never did. The doc mentioned reducing side effects this way but I would love to know what the mechanism for that would be, since estrogen suppression is the cause of side effects, presumably.
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@windyshores Thanks for the response. You make a good common sense point about the side effects being caused by the result rather than the med. None is none as far as estrogen is concerned. I see another comment after this about the reduced dose causing less side effects so I guess I need to do some research. Like your earlier comment though, it would probably make me nervous to reduce the dose. If it ain’t broke don’t fix it.