← Return to Double mastectomy /Estrogen positive DCIS and increased arthritic pain

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@cathyn

The difference in your case is that you had your ovaries removed. They are the main source of estrogen production. You still have very small amounts and estrogen is stored in fat tissue, but with double mastectomy and ovaries removed it would not seem that you need an estrogen blocker afterwards. There are significant issues with them, not just uncomfortable side effects. It isn’t black and white, but I don’t think you got bad advice from your first doc.

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Replies to "The difference in your case is that you had your ovaries removed. They are the main..."

@cathyn @snowdon @californiazebra Indulge me if you know this, but aromatase inhibitors address estrogen made by the adrenal glands, not the ovaries or in fat.

If ovaries were removed, I believe that aromatase inhibitors can be used instead of Tamoxifen.

Many of us do not have significant issues with these meds but bones need to be monitored.