A few remarks - To jump the gun, some people on Reddit have been buying Pirenzepine from Japan and taking it orally and some have been making topical creams. Someone on Reddit claimed it worked after taking it orally for 45 days. Others have not see the same results. Also Pirenzepine can result in stomach pain so it should only be used with caution. I also understand (second hand) that the reason Winsantour are doing it as a cream is that they believe that the concentration needed to make it work orally are so high that it can only be applied topically.