Four medicines that work for me for depression, anxiety, and fatigue are:
depression: methylphenidate (Ritalin)
depression: buproprion (Wellbutrin) - a norepinephrine and dopamine reuptake inhibitor
anxiety: clonazepam (Klonopin)
fatigue: rivaroxaban (Xarelto) - off label use of a blood thinner

It took my doctor and I ten years to find this combination.
Best wishes.