I have tried over 6 anti-depressants. ALL have made me feel worse. I just cannot take them. The only thing that has helped my panic disorder is Klonopin, a Benzodiazepine. It’s a little tricky because of the chances of dependency if you take it for too long. I was taking a VERY small dose—-.25 mg/day. Right now I’m slowly weaning off, and I’m controlling my anxiety by exercising. I go to the gym most days, and I feel much better. There are a myriad of natural ways to help yourself….good luck!