Anastrazole and anxiety

Posted by momandrph048 @momandrph048, Jun 14, 2023

Has anyone else taking an aromatase inhibitor been dealing with crying very easily, and anxiety that comes out of nowhere?? It doesn’t seem to be related to anything, it just appears out of the blue.. My oncologist has me on Effexor, but it doesn’t seem to be doing that much and I really don’t want to increase my dose.. Can anyone share a similar story? Counseling isn’t really for me, I just need to deal with it on my own, and I really feel that the medication is the reason for it.. Mostly because my dr had me stop it for a couple weeks due to joint pain and everything got better.. Thanks for your input!

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@nora305

I came down with anxiety and depression, not to mention bad joint and muscle pain, when I was on Letrozole. I have been switched to Anastrozole and am now also taking Lexapro to handle the emotional symptoms of this drug. I initially fought going on Lexapro, but I decided that I needed to do whatever I could to stay on my aromatase inhibitor. Good luck with your own journey!

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I too was on lexapro after very serious brain aneurysm. If I can do it you can stay on anastrazole. Stay in the company of those that make you happy. Be good to you. This anxiety will pass.

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@nanna1948

I too was on lexapro after very serious brain aneurysm. If I can do it you can stay on anastrazole. Stay in the company of those that make you happy. Be good to you. This anxiety will pass.

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Thank you so much, this was exactly what I needed to hear today.. 🌸

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I am so happy I could be of help. It is a scary road but totally doable.

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Your situation is similar to my past experience.. I was treated for breast cancer Her2+ hr - I had chemo therapy and radiation. After this period I was put on Anastrozole for 5 years . I too had anxiety and cried at drop of a pin. I was put on Effexor (still am many years later).
I found Effexor to relieve my anxiety and have no wish to get off of it in fear my symptoms come back

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Dear Momandrpho48
I was having the same issue on Anastrozole. It was called Brain Fog on the list of possible side effects.
Mentally I was just not me. I cried when alone and felt like I was saying ‘who is this person?”

In my research as to why I was experiencing such joint and muscle pain in my knee, I read how blocking estrogen for the sake of
breast cancer made me think of rephrasing the saying - damned if you don’t (take Anastrozole) - damned if you do. I learned that your brain and jounts/muscles are 2 vital parts of our bodies that estrogen plays a very important part and was being denied . While I didn’t go on my current hiatus because of brain fog, it has become one of the changes that I am most aware of and grateful for. As with the incremental recuperation from muscle/joint pain , the brain fog recovery isn’t instant but is very evident.

Just wanted to share what seems to be our similar experiences with Anastrozole and hope it helps you.
I have found it a problem that in order to alleviate a side effect of Anestrozole, we are prescribed or made aware of another drug to include in addition.

You seem very aware of yourself. Stay strong and remember you reached out here when you rightfully questioned what was going on. You can get comfort from this group but you more importantly can be made aware.
I hope you will stay tuned! ❤️

All the very best!
Gini

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I took Aromasin (Exemestane) for about 5 months after a DCIS diagnosis. My mood was definitely impacted. I could cry very easily and my anxiety worsened. As someone who already deals with anxiety I found this to be very difficult. I just over all did not feel well. As my risk of recurrence is very low ( I had surgery and radiation) I decided to stop the medication. I try to exercise daily, try to eat better and leave it at that. My situation is not everyone's situation of course, but this decision is the best for me. I agree that adding a med to tolerate a med seems strange, but if it works then that plan is best for individual patients.

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I think we cry easily, have brain fog, etc, because the AI’s and Tamoxifen put us into a menopausal state. Perimenopause and menopause were horrible for me and yet here I am. I do use cbd to help me sleep and that has made a difference. Everything seems better when we are getting good sleep. Hopefully, over time the side effects will get better. ❤️

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I was on Anastrozole for 5 years for my breast cancer. I truly had no side effects from it . I was prescribed Effexor for anxiety which I still take 7 yrs later. I’m afraid to get off of it for reasons of side effects ( dizziness and lightheaded) and what to expect about my anxiety

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I am 1 year into anastrozole for my breast cancer. My side effects are about the same. Headaches joint and muscle pain. Do I cry sometimes when sitting by myself. I try to keep myself busy and think of other things.
I take my pill at dinner around 6 or so no caffeine after 2 and been drinking sleepy time tea at night to help me sleep around 7:30 or 8:00. That seems to help me. By the way I do get up 4:30 a m for work.

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@ginip

Dear Momandrpho48
I was having the same issue on Anastrozole. It was called Brain Fog on the list of possible side effects.
Mentally I was just not me. I cried when alone and felt like I was saying ‘who is this person?”

In my research as to why I was experiencing such joint and muscle pain in my knee, I read how blocking estrogen for the sake of
breast cancer made me think of rephrasing the saying - damned if you don’t (take Anastrozole) - damned if you do. I learned that your brain and jounts/muscles are 2 vital parts of our bodies that estrogen plays a very important part and was being denied . While I didn’t go on my current hiatus because of brain fog, it has become one of the changes that I am most aware of and grateful for. As with the incremental recuperation from muscle/joint pain , the brain fog recovery isn’t instant but is very evident.

Just wanted to share what seems to be our similar experiences with Anastrozole and hope it helps you.
I have found it a problem that in order to alleviate a side effect of Anestrozole, we are prescribed or made aware of another drug to include in addition.

You seem very aware of yourself. Stay strong and remember you reached out here when you rightfully questioned what was going on. You can get comfort from this group but you more importantly can be made aware.
I hope you will stay tuned! ❤️

All the very best!
Gini

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Thank you so much! It helps to know I’m not alone!

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