I have migraines, up to 15 per month. Both Topamax and Lamictal (Lamotrigine) caused me to have seizures. Never experienced seizures in my life, but after increasing the anti seizure medications above 100 mg. per day, I developed seizures, up to 3 a day, lasting 10-15 minutes. My neurologist said he had never had a patient with this is reaction to Topamax. Seizures stopped within 2 days of discontinuing meds. After discontinuing Topamax, migraines increases to chronic, daily. I now take 240 mg. of Verapamil and 30 mg nortriptyline. Migraines have improved to 10-15 a month, and much less severe.