Hi, I'll weigh in about the blood pressure drop. Your BP numbers are my numbers. Anyway, Tymlos will reduce your blood pressure -- that's what accounts for the tachycardia. ( If you haven't read about that part, welcome....) The increased hear rate is your heart is trying to make up for the drop. Anyway, to deal with the tachycardia, which is distressing but apparently not dangerous, the Tymlos nurse recommended that I lie down and elevate my legs. It absolutely works. Yes, it turns the injections, which take seconds, into "a thing" that can last 15 minutes for me, but it's worth it. I generally inject before going to bed so lying down doesn't become too big a deal. Good luck on Tymlos. I found it a difficult adjustment. I am 3 months in and only up to 4 clicks, occasionally 5. Ramp up slowly.