← Return to Remedies for Joint Discomfort/Pain on AI ( Anastrozole)

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@californiazebra

I'm curious about your joint pain from an AI. Location(s)? How long were you taking an AI before the pain started?

I have been on Letrozole for 27 months for MBC and only started having knee and shin pain in the past few months and mostly at night once sitting or lying down. I was worried the cancer may have spread to my bones, but was told it was the AI causing symptoms. How does my oncologist know that since the pain was not immediate?

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Replies to "I'm curious about your joint pain from an AI. Location(s)? How long were you taking an..."

I have always had a low level discomfort but at 12 mos ( now 14) it presented much stronger… overall but more intensely felt in hips and hands.

I can see how bone pain can be confusing and anxiety provoking with MBC but your oncologist is your best guide here. Best to you and to all of us on this unwanted journey.

Also at night or when resting… maybe more aware? But it can wake me up as well.

I went months on Anastrozole before my right knee became horribly disabled. Once I stopped taking Anastrozole it is taking months to go away- but it is getting there. The research I have had to do to figure out what was going on seems wrong. Glad you came here to get input. I have connected with some valuable input.

I had very similar reactions was on Anastrozole for almost a year before I had leg/knee pain in my right leg. Tried very hard to deal with it but currently on a 3 month hiatus from taking Anastrozole. I was concerned when results regarding many side effects have dissipated but leg/knee issues seem slower to ebb. As usual, I was given no heads up as to what to expect so I have returned to my self investigation. It seems that there are side effects that take a longer time to show progress returning to normal - or at least a tolerable situation. In the meantime I am walking and have scheduled Physical Therapy (The jury is still out on this but worth trying).

As this point the pain has gone from constant to intermittent. I will continue to work on a achieving the quality of life that I remember before taking Anastrozole

Please share your experience as you go along. I would be so interested as I am sure others would be ❤️

I had joint pains from Anastrozole. Went off it per doc's advice and started taking glucosamine & chondroitin supplements till pain went away. Now on exemestane; no pain

Yes! Exactly what happened to me. Had the frantic feeling also that something bad was happening. Since I was provided a prescription immediately after surgery without what should have been an in depth discussion, i began researching myself. Found it was not unusual for leg/knee issues. I was told after several medical inquiries that ibuprofen/Bengay were reliable solutions. NO THEY WEREN’T. I am on an agreed to 3 month hiatus. No mention of what to expect. While several other side effects have gone - my leg/knee limitation is very very slow to ebb. Again my research provides info that says indeed this particular side effect is much slower to show results. And so it goes. I am very disheartened in this situation but remain hopeful time will tell. It is said that misery loves company. It is indeed comforting to care and share. Stay positive.

I was on Anastrozole for a year before my knees started bothering me. Within a few months after that onset, I felt practically crippled. I then switched to Letrozole and started collagen supplements. Within a few months the pain was gone. I think it was the collagen rather than the Letrozole switch as a few months later I mistakenly bought a supplement without the collagen and noticed the aches beginning to return. Walking helped with back pain.