I posted something a while back about positioning. See photo.
Since then I bought the UGO brand Flip-Flo Valve. The brand is important as others slip out of the port. A real game-changer. Here are some options:

Position upward or off to the side using your pants waistband to hold it in position.

Wear "sporty" pants as much as possible, the darker the color the better-just in case . . .
loose black all cotton gum pants with the tie string or elastic waistband are the best with a casual shirt to wear over the port or tuck the shirt in. Loose pants don't move the tubing as much as tighter-fitting kinds if you need to use a leg bag. I do not wear underwear with this option- ever notice when you're not wearing anything that it doesn't bother you as much?
Same principle.

Buy those adhesive clips that stick to your leg to hold the tubing in place if you need a leg bag and underwear, boxer briefs have been reported to work for this setup.

However, there really is no way to avoid all discomfort. I've had my bad days, particularly during a UTI.

All in all, I myself have skipped over all that with a few nice pair of loose-fitting black all cotton gym pants without underwear if I'm using a leg bag. If I don't use the leg bag I use the waistband to hold the port end with a Flip-Flo Valve in place, so I can work out in the gym, go jogging. I cover it with any shirt and no one sees it and I don't have any discomfort because the tubing is not moving, causing any friction in the urethra.

Hope this helps get you started to finding a good solution that's best for you.
PS- the picture in my previous post shows the "tap" closing the port with a clip I used to prevent dropping or losing it in public, it only shows the positioning.