Are you taking Reclast for osteoporosis?

Posted by Becky, Volunteer Mentor @becsbuddy, Jul 21, 2020

Two years ago I was diagnosed with pretty bad osteoporosis because of the prednisone I was on for my autoimmune disease. I started taking Fosamax (a bisphosphonate) and had no problems. Today, the endocrinologist suggested that I switch to Reclast for 3 yearly infusions. Has anyone else taken this drug? What side effects have you had?
Thanks

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@windyshores

@bruceandruth1970 the protocol is below (and posted previously by another poster). Please note that this dose of strontium throws DEXA scans off, and also that strontium is not without risk (at least the ranelate form).

Vitamin D3 2,000 iu daily
Fish oil Dha 250 mg daily
Strontium Citrate 680 mg daily
Magnesium 25 mg daily
Vitamin K2 100 mcg daily
Dietary consumption of calcium
Weight bearing exercise

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Don’t take strontium ranelate. It’s completely different than strontium citrate. It’s explained on internet. Ranelate is dangerous. Can cause heart problems. I don’t care about Dexa scans. Who’s to say if they’re accurate. Even getting a scan on different machine changes the results. I’m worried about fixing my spine and I’ve made my choice. Everyone needs to research. Pharmaceutical companies charge thousands of dollars for infusion drugs. They don’t want us to use vitamins and minerals proven to improve osteoporosis.

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I agree with you. FDA acknowledges about thigh fractures. Everything you said is correct. Your body stops removing dead bone and building new bone. These drugs put a coating over your bones. I read if you fall your bones will shatter like glass

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I have had several infusions of Reclast with no side effects or problems.

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@windyshores

@ymv I did not start with a full dose. The first dose I took was the full 80mcg and I landed in the ER (preexisting afib). I was determined to take itand started at two clicks out of 8 and ramped up. I mostly take 7 clicks, sometimes 6, a few times the full 8. I have had excellent gains with a partial dose and my doc approves.

Side effects do ease over time as your body adjusts to it. Some days I have none, and some days I still have them even at 7 clicks. I have learned it is better to get up and out in the morning after I take it. I do not take it in the evening because I am more prone to afib then. (Haven't had any since...)

Side effects for me include the brief rapid heart beat (better after a month or two), nausea (better after a month), headache (also eased) and the most long lasting has been fatigue, which, again, I counteract by going out and doing what I need to do. It is worth it! Or has been for me. And some people have NO side effects. I am extraordinarily sensitive to a lot of meds, have several other conditions, and am small in size.

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@windyshores
I appreciate your reply and information. Last night was my first dose and I experienced mild nausea and headache about an hour after administering a full dose. Am keeping my fingers crossed for ongoing treatment. After you complete your full course will you start/resume Prolia?

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@ymv

@windyshores
I appreciate your reply and information. Last night was my first dose and I experienced mild nausea and headache about an hour after administering a full dose. Am keeping my fingers crossed for ongoing treatment. After you complete your full course will you start/resume Prolia?

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@ymv If nausea and headache are too bad, go down one click. For a week or two. I almost never took the full dose and still got good gains. But of course it is optimal to take the full dose and it sounds like you will be able to without significant side effects. You do have the option of reducing and then ramping back up!

My doc does not prescribe Prolia and I have never taken it and never will. That means Reclast at some point anyway!

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@rtelega

Don’t take strontium ranelate. It’s completely different than strontium citrate. It’s explained on internet. Ranelate is dangerous. Can cause heart problems. I don’t care about Dexa scans. Who’s to say if they’re accurate. Even getting a scan on different machine changes the results. I’m worried about fixing my spine and I’ve made my choice. Everyone needs to research. Pharmaceutical companies charge thousands of dollars for infusion drugs. They don’t want us to use vitamins and minerals proven to improve osteoporosis.

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@rtelega it is important that people know the effect of strontium on DEXA's because people post about their gains while on strontium and other people read it. But I agree with you that DEXA's seem to fluctuate anyway- I look for trends.

Tymlos, the one I have been taking, is not an infusion drug. I inject it daily. I am so grateful for it. With 7 spinal fractures I could not waste any time and I think the COMB protocol would not work fast enough or intensely enough for someone like me.

The pharmaceutical company, Radius, gave me Tymlos for free through their patient assistance program so they didn't make money on me, they lost it 🙂

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To all-when combo protocol was mentioned I thought it was going to be something I had heard about , but it was not .HOWEVER, I tripped over this video of information and maybe you can as well . it was from a Dr. Benjamin Leder , an endocrine dr from Mass General Hospital , the title was" Combined and Sequential Approaches to Osteoporosis Therapy." It was very interesting and informative. Studies of what meds they've used together , and different sequences of them. Plus he discussed where they are at in the development of new drugs, which was a bit dismaying , as he stated there isn't a lot going on to look at researching new med options. I feel sad about that . Makes me think they feel like what's out there is working and the best they can come up with , which I think many on this forum clearly would disagree with!!!! Hope you can find this information if you're so inclined!

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@ans

To all-when combo protocol was mentioned I thought it was going to be something I had heard about , but it was not .HOWEVER, I tripped over this video of information and maybe you can as well . it was from a Dr. Benjamin Leder , an endocrine dr from Mass General Hospital , the title was" Combined and Sequential Approaches to Osteoporosis Therapy." It was very interesting and informative. Studies of what meds they've used together , and different sequences of them. Plus he discussed where they are at in the development of new drugs, which was a bit dismaying , as he stated there isn't a lot going on to look at researching new med options. I feel sad about that . Makes me think they feel like what's out there is working and the best they can come up with , which I think many on this forum clearly would disagree with!!!! Hope you can find this information if you're so inclined!

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Great video @ans. Thank you!

It really shows the blunting of the effects of anabolics by using anti-resorptives first (often required by insurance). The standard of practice dictated by insurance needs to change!

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@windyshores

@ymv If nausea and headache are too bad, go down one click. For a week or two. I almost never took the full dose and still got good gains. But of course it is optimal to take the full dose and it sounds like you will be able to without significant side effects. You do have the option of reducing and then ramping back up!

My doc does not prescribe Prolia and I have never taken it and never will. That means Reclast at some point anyway!

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@windyshores , I’m curious why your doctor doesn’t use Prolia and why you would never use it? It’s often so overwhelming to research information about osteoporosis treatment as no treatment is without negative factors.

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