Maximum daily amount of B12 one can take

One thing to add: B12 shots alone may not do enough. I needed to take 5000mcg orally daily to get my levels up (the CVS chewable 5000mcg worked fine). One of my neurologists, Dr, Oaklander, said she wanted my levels to be 600-1000. They are now over 1,000 most of the time when I get tested.

BTW so far it's not helping anything and my foot neuropathy is still gradually getting worse.

Hi @mariannelarsen, Welcome to Connect. It's great that you are doing your own research and learning as much as you can about your condition. I think all of us have been there in the I'm a mess state. What really helped me get out of it was finding Connect when I was first diagnosed with neuropathy and learning as much as I can about the condition and treatments that may provide some help or slow the progression. If you haven't already seen it, you might want to bookmark the following site and browse through the information and the videos on their webinars page here - https://www.foundationforpn.org/past-webinars/.

Which neuropathy symptom bothers you the most?

Well I finally got an answer to my neuropathy Apparently I have Multiply Myeloma - not good I am going to an hematologist/oncologist and get some more information.

Who told you that cancer causes neurological disorders?

Kappa lambda light chain blood report - abnormal and neuropathy in feet. On my way at this moment to hematologist/oncologist

Here is a quote from an article I"ll reference. The whole article is easy to read and fairly non technical: "A serum vitamin B12 level between 200 pg/mL and 900 pg/mL is considered normal, but a threshold of 300 to 350 pg/mL is recognized as a marker for a desirable status in the elderly. The laboratory diagnosis is usually based on low serum vitamin B12 levels or elevated serum methylmalonic acid and homocysteine levels. Elevated homocysteine is an important marker for vitamin B12 and/or folate deficiency. Classic deficiency symptoms such as megaloblastic anemia often fail to appear with subtle deficiencies, as they are usually late clinical signs of severe deficiency.3,4 Symptoms of vitamin B12 deficiency include anemia, neuropathy, and neuropsychiatric disorders."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781043/#:~:text=A%20serum%20vitamin%20B12,methylmalonic%20acid%20and%20homocysteine%20levels.
I would be interested in knowing why Dr. Oaklander wanted your B12 level to be higher than normal. You might ask her to direct you to references that support that idea. Your's is only one case (although it's certainly the most important case to you!), and doesn't prove anything, but notice that even at higher than normal levels, you have noted no improvement, and the disease progression continues. It is possible that B12 has nothing to do with your form of PN.
At this point in time, PN is an extraordinarily difficult and frustrating disease. Hopefully, that will change in the future. This situation affects everyone: patients, doctors, families, etc. Do the best you can, stay informed, and try to have a positive attitude.

My Vitamin B12 level was slightly high so I changed my multivitamin to one that wasn’t 200% of the daily RDA. Here has been no change in the neuropathy of my feet, I am a meat eater and don’t believe I have cancer. My neurologist doesn’t know what caused my neuropathy.