I've had cryoablation 3 times for spots on my lungs. They have been so small that they can't even get a biopsy but assume they are cancerous from colorectal colon cancer. Dr. Buckley has done the procedures at St. Lukes in Kansas City. This procedure isn't too bad, some pain for a few days but much better than full surgery or Chemo/radiation. I hope your procedure goes well. My Signatera test went from 0 to 0 to .04 to .06 to 1.13 to 5. So far they have only found the 1 spot that was cryoablated. So I hope my next test will go back down. We will see- keeping my fingers crossed.