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High or Fluctuating Chromogranin A Level: What does it mean?

Neuroendocrine Tumors (NETs) | Last Active: Jun 18 3:39pm | Replies (184)
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@peg152

My Chromogranin A was 1507 last year and the PET was negative. In February I was hospitalized with a liver abscess with a spot on the pancreas and lung. Was on Zosyn for 6 weeks and two weeks of amoxicillin and Cipro when that was done. No stomach meds for months and my Chromogranin A is now 1414. Going back to the cancer doc for another possible PET. Scary having such a high number on this test without n owing why.

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Replies to "My Chromogranin A was 1507 last year and the PET was negative. In February I was..."
Teresa, Volunteer Mentor | @hopeful33250 | Jun 19, 2023

Hello @peg152 and welcome to Mayo Connect. Your concern is certainly understandable. The strange thing about Chromogranin levels is that they can be high, but not necessarily be indicative of cancer. Other factors can raise these levels as well.

I certainly agree with your decision to check with a doctor, though. This is a good place to start. Have you had a diagnosis of cancer previously? I'm also wondering, given all of the problems you mentioned, if you have had any biopsies?

How are you feeling? Do you have problems eating or problems with digestion, such as diarrhea, constipation, vomiting, etc.?

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