It's been almost two months on Quilpta which is the same thing as the injectables in pill form. I was on 30 mg but the constipation and the hair loss was so bad she had me half the dose at 15 mg. A lot of people are on 60 mg. So far the 15 mg is working for my hypnic headaches and the constipation is so much better. I still wake in the morning with a slight headache which a cup of coffee takes care of. I can't take Miralax which a lot of people take because the PEG gives me awful headaches.

Yes, Avjovy and Emgaloty have helped with my Migraines, but NOT at all with my nocturnal "Hypnic" type headache. I took Emgality for several years (it worked AMAZINGLY well on migraines along with many migraine sequelae such as color distortion, visual distortion and sensitivity to light, and almost cured my severe dry eye syndrome). However, I was paying out of pocket and when my insurer finally adden one CPRP to the formulary, I switched to Ajovy. It works almost as well to prevent migraines but less well on the accompanying sequelae. NEITHER of these two drugs had any impact on my headaches generated by nocturnal REM sleep. I have had to continue Indomethacin plus coffee, though now on a lower dose of Indo with the addition of high dose melatonin also prior to bedtime. I hope found a treatment that helps, and that you are feeling better.