Can Prolia be safely and reasonably discontinued?

I also am hoping that I can continue to be off of Prolia after my one year of Reclast. I still have the muscle and joint pain but I do not want to take anymore of these medications (biphosphonates) I am hoping we can continue to share information and walk each other through this.
Good luck to all.

I don't understand some of the comments regarding Prolia "infusions". I've been on Prolia for 5 years and it's always been administered to me in a simple injection.

Also, I did stop Prolia for 3 months in anticipation of a root canal and it was a mistake as I spontaneously fractured 2 thoracic vertebrae. In horrible pain and had to wear a brace for 3 months. Had to have kyphoplasty. If you go off Prolia, from what I've read, you need to go on a bisphosphonate.

Is there a doctor in the St. Louis area or at Barnes Hospital that is a specialist in getting off of Prolia?

I recommend Dr. McCormick and his book: MD's don't seem to do the blood tests that determine the best timing for the Reclast follow-up, though maybe you can find one who will.

I read where prilia is lifelong because if the rebound fractures. Would need a relay med after? Is Fosamax an option? Or actenol or Evista?
I just started Fosamax, worried about jaw decay, go to dentist in July for my 6 month. I don't want prolia or reclast, can't afford evenity or other anabolic, but you still have to relay to another osteo med after these too. It's a vicious cycle. I take calcium, d3, k2, magnesium, exercise , increased protein. I'm 66 and have osteoporosis and a back surgery in 2023 with hardware.
I researched Evista, going to ask Dr about that. Doesn't have jaw decay, but has a risk of possible blood clots and hot flashes.
Good luck to all.

Thank you for your information. I would like to know why you do not want to take Reclast. I am about to start Reclast because I need to try and address having stopped Prolia. I took Prolia for one year and then Reclast for one year, but I have been off of Reclast for two years and my dexa scan shows that I am worse off than I was before I took the Prolia, so dr. says I have to go back on Reclast. This is very frustrating. thank you for your help !

Reclast is one year infusion and I'm worried about side effects since that med is in the body for a long time being yearly. I'm assuming you didn't have any side effects from reclast since you took it for a year? But you had side effects from Prolia? If you did good on Reclast, seems like that would be the med to stay with? It's a journey being on these meds, and everyone reacts differently to them, some have side effects, some not. But seems like once you're on one, it's lifelong since you have to change/ relay to another osteo med when stop one. I just started Fosamax, I'm worried about the jaw decay and I'm having bone and muscle pain and fatigue. I need something to help my bone density but I'm feeling worse now than I ever did without these meds.

I understand how you feel. I am so very sorry that I took Prolia. I felt much better before I took Prolia. I resisted taking it for two years and my endocrinologist kept telling me I needed to take it so I finally decided to take it. I listed all of my questions before I took it and I was told repeatedly and by each of my doctors that there was nothing to worry about. I am now on the roller coaster of having to take a medication to counter the rebound from stopping Prolia. I know everyone reacts differently to these drugs, but I have been dealing with the side effects and rebound of taking Prolia for years now. At present I am waiting for my fractures of my sacrum to heal so I can go back on Reclast. Reclast seems to be the best choice for now. My heart goes out to any of you who are in this situation. I wish I had listened to my "gut" feeling, that there were too many unknowns about how I would react four years ago, when I first started Prolia. Wishing you all the best !