I've been trying to go down on my Prednisone. To that effect, my rheumy started me on Methotrexate (1 X weekly, 10 mg at first and now 15). I went down from 15 mg Prednisone to 12.5 to 10. However, my PMR has flared up significantly, again with the upper and lower body aches and stiffness. So I've gone back to 15 mg Prednisone again and we'll evaluate whether to stay on MTX in another month. I do have Smoldering Myeloma and the doc thinks its a complicating factor in conrolling the PMR.