I had a reclast infusion 1 year and doc is scheduling another infusion soon. FYI...I had terrible reaction. Bone and muscle pain like nothing I have ever known. I spent two days in the hospital for pain management. The doc wants me to come in for consultation before the infusion this year. I am I can be hospitalized this time from the the begining. Drink plenty of water for a couple days before. Check into taking tynol before and after. Request the infusion be administered in 30 to 45 mins. Not the usual 15 min time frame. Some ppl have this infusion with no problems. Wishing you all the best!!