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tricyclic antidepressants

Digestive Health | Last Active: Jun 17, 2023 | Replies (9)

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@seabright2001

I recently started taking nortriptyline for IBS-D and am finding it helpful. I also found Imodium to be more effective than lomotil for me and it is available by prescription if you do not like dealing with all that packaging and the small quantities available over the counter. Don’t be afraid to try the FODMAP diet, it’s not as hard to follow as you might think. I also started taking a probiotic. Overall, I’m doing much better but, unfortunately, there’s no cure for this condition.

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Replies to "I recently started taking nortriptyline for IBS-D and am finding it helpful. I also found Imodium..."

Hello @seabright2001 and welcome to the Digestive Health support group on Mayo Connect.

I really appreciate your post. It sounds like you have been very proactive in trying different meds as well as dietary changes to deal with an uncomfortable condition. It is important to seek the help of our medical team but to also try lifestyle changes, such as you have done with your diet.

I, too, have found daily probiotics to be very helpful as well as dietary restrictions. For me, a low residue diet is very helpful. As you mentioned, the FODMAP dietary plan is extremely helpful to many of us.

I look forward to getting to know you. Could you share how long you have been dealing with this problem? Any other medical tests that have been helpful with the diagnosis?

Thank you for your reply. It is encouraging to read that you are much better taking nortriptylene and imodium. I have been relucant to go on medication other than occasionally taking hyosciamine and anti-diarrheal because I don't have urgency and diarrhea all day long. It is usually in the morning if I eat anything (doesn't seem to matter what I eat). With that said, it is daily and I don't like to plan my morning around a bathroom. I think I will talk to my GI again about a tricyclic medication. I understand the biological mechanism and how it can be helpful even if you are not depressed. I will also try the fodmap diet again too and try to be more disciplined. I really love onions, garlic, etc. (haha)
thanks again