As edmond1971 says, any more clinical data you can provide may assist the forum in providing assessment and feedback.

With what you describe, it would seem doublet or triplet therapy may be something to discuss with your medical team. Here's a link to start your literature search - https://pubmed.ncbi.nlm.nih.gov/37055323/

If you have a radiologist on your medical team, they should be part of your decision making process.

Here's my clinical history, I had triplet therapy starting in Jan 17, recently, we're doing doublet and holding Xtandi in reserve pending PSA results at the end of July. If it goes down again, don't add, if it doesn't, we'll consider adding Xtandi, an ARI.

It is likely your advanced PCA cannot be "cured." You ay have to manage it is a chronic disease with a whack a mole approach. Perhaps think in terms of 3-5 years, will this treatment work for the next 3-5 years, if so, great, because then there will be new treatment choices. as medical research continues.