Good evening @uhenze. I notice that this is your first post and want to make sure that I am reading the correct words. Would you please post a reference to the "discovery" of Duloxetine as the worst thing to take for neuropathy? I was given a prescription for Duloxetine after tapering off of a night-time medication. My instructions were to take the Duloxetine in the morning. Over the last four years.....my daily dosage has been increased to 120 mg. None of my clinicians including those in neuropathy and endocrinology have indicated that this medication is unhelpful for neuropathy. I have been struggling with SFN (small fiber neuropathy) for about 10 years. Please help me understand the reasons for the negative comment.

Has your clinician recommended a replacement? Have you found one on your own?

Thank you,
Chris