This is Golfy. I also started on big 3 two weeks ago. I take them Monday, Wednesday and Friday. I have no idea what to expect. I have had a little queasy after I go to bed. Forgot to say that I take them two hours before bedtime. The last two mornings I have felt totally wasted, kind of dopey, I just sit. Not sure if it is from the drugs or from the disease. I am totally confused about all of this. Sorry if I sound negative; don’t mean to. Will mention that I am 90 years old. I would think old age would make it more difficult. I will keep you posted on my situation, and I wish you all the best with your health issues.