Scientific studies have shown that for intermediate risk localized prostate cancer androgen deprivation therapy makes no difference in biochemical reoccurrence or overall survival in men over 70 and I am 74. I did not take the six-month Lupron shot as I self-castrated. I have been on testosterone replacement (Androgel) since 2008 when I stop my testosterone level drops to castrate levels in 60 hours. My radiation oncologist didn't believe me and had me tested and it came back at 12 ng/dl which is lower than a Lupron shot does according to their website. Why did I do it if it makes no difference? Just hedging my bets on a favorable outcome. If the PC does come back by then I will probably be 79 and it probably won't kill me anyway and I will die of something else anyway.