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Tagrisso and Hives

Lung Cancer | Last Active: Jan 12 5:17pm | Replies (19)

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@privatenurse

I think September is too long a wait. You can do this with photos & a video appointment. There are ways to get someone back on Tagrisso after it was discontinued following wakening with itching, that morphed into burning by noon of day 3 on the drug. Seems very similar to your issue.
One is trying doxepin, if that alleviates the burning, in this case, the Tagrisso can begin again. If doxepin is not well tolerated, as in this case, gabapentin can be utilized in the same manner. Eosinophils were elevated in bloodwork, which indicates allergy. Lung oncologist was comfortable with it.
Once on the Tagrisso, the gabapentin can be tapered off of slowly or you might choose to stay on it or taper to a lower dose.
A dermatologist was the physician working on this.
There are many antihistamines. Also strengths of hydrocortisone cream.
If this is unintelligible, I'm sleep deprived.
The url Matthew K. posted is not only hot of the presses, but Tagrisso achieved unprecedented survival in early-stage EGFR-mutated lung cancer, with 88% of patients alive at five years in ADAURA Phase III. Keep the faith, Ms. Whahoo.

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Replies to "I think September is too long a wait. You can do this with photos & a..."

Hi @privatenurse. Thank you for the kind response. After day 2, I stopped Tag to let the hives clear up. Per my oncologist I restarted Tag this morning and we’re going to do it every other day to see how I respond to it. If I get covered in hives again, I’ll push up my dermatology appointment.

I take Lyrica which is a gabapentin alternative. I’ve been on it since I had my right upper lobe removed. Don’t remember then name of the antihistamine but it’s good at putting me to sleep. And I have a tub of white steroid cream. It doesn’t seem to do much.

So far it’s been 6 hours since I took Tag. Knock on wood … no hives yet.