I have was diagnosed with recurrent prostate cancer Gleason 9 (4+5) Grade 5 last summer. I had surgery over 15 years ago, but now the cancer spread to the bladder. I started on Eligard and Abiraterone last fall and continued through my radiation treatment that ended in April. I found the side effects from ADT to be overwhelming. Most significant for me was depression and anxiety that made it difficult for me to function on a daily basis. I made the decision to stop the Abiraterone first and then decided not to continue with Eligard after my last 3 month shot. My doctors agreed considering that my PSA was undetectable, and my testosterone is zero.

If your PSA is undetectable, I don't think there is any problem with stopping ADT. Many people go on intermittent hormone therapy and resume treatment when the PSA climbs to a certain level. Your testosterone will slowly come back, and your doctors will monitor your PSA to see if you need to resume ADT. You can opt for a "milder" treatment next time around. Talk to your doctor about Casodex instead of Lupron. The side effects are less intense.